Open AccessComparison of dexmedetomidine versus propofol-based anaesthesia for controlled hypotension in functional endoscopic sinus surgery
Author(s) -
DK Bharathwaj,
Shaila S Kamath
Publication year - 2019
Publication title -
southern african journal of anaesthesia and analgesia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.175
H-Index - 10
eISSN - 2220-1173
pISSN - 2220-1181
DOI - 10.36303/sajaa.2019.25.2.2051
Subject(s) - dexmedetomidine , medicine , propofol , functional endoscopic sinus surgery , anesthesia , mean arterial pressure , heart rate , blood pressure , hemodynamics , surgery , endoscopic sinus surgery , sedation , sinusitis
Background: Increased intraoperative bleeding during functional endoscopic sinus surgery (FESS) affects operative field visibility, which increases both duration of surgery and frequency of complications. Controlled hypotension is an anaesthetic technique in which there is deliberate reduction of systemic blood pressure during anaesthesia. The aim of the study was to compare the efficacy of dexmedetomidine against propofol infusion when used for controlled hypotension during FESS.Methods: A randomised, prospective, and single-blinded study was carried out, which included 80 patients of either sex of ASA grade І & ІІ who underwent elective FESS. Patients were randomly assigned to two groups: Group A (dexmedetomidine), Group B (propofol). Intraoperative mean arterial pressure (MAP), heart rate (HR), surgical grade of bleeding (based on the Fromme– Boezzart scale), and amount of bleeding were recorded.Results: Groups were well matched for their demographic data. There was a statistically significant difference (p 0.05) in terms of surgical grade of bleeding between Group A and Group B.Conclusions: Both dexmedetomidine and propofol infusion are efficacious to facilitate controlled hypotension and haemodynamic stability intraoperatively.