Open AccessMarkers of viral hepatitis E (Hepeviridae, Orthohepevirus, Orthohepevirus A) in the imported Old World monkeys
Author(s) -
Dmitriy I. Dogadov,
Л. И. Корзая,
К. К. Кюрегян,
Anastasia A. Karlsen,
М. И. Михайлов
Publication year - 2021
Publication title -
voprosy virusologii
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.151
H-Index - 15
eISSN - 2411-2097
pISSN - 0507-4088
DOI - 10.36233/0507-4088-34
Subject(s) - hepatitis e virus , biology , virology , genotype , antibody , serology , feces , virus , primate , transmission (telecommunications) , hepatitis e , hepatitis , immunology , microbiology and biotechnology , gene , genetics , electrical engineering , neuroscience , engineering
Viral hepatitis E is a zooanthroponotic disease that occurs in humans and various animals, including monkeys. It is caused by hepatitis E virus (HEV) (Hepeviridae, Orthohepevirus: Orthohepevirus A), for which 8 genotypes have been described to date. Among them, strains of genotypes 1 and 2 have been isolated from humans, strains of genotypes 3 and 4 from humans and animals, and strains of genotypes 5-8 from animals only. The main threat of the disease is associated with the documented zoonotic transmission of HEV genotypes 3, 4, 7, and 8, to humans through infected meat, blood and milk. Thus, monkeys could be involved in the transmission of HEV.The aim of this work was to study serological and molecular genetic markers of HEV infection in strepsirrhines (Old World monkeys, Cercopithecoidea), imported to the Adler Primate Center from various regions of the world (Tanzania, Vietnam, Mauritius).