Synthesis and characterization of human rotavirus A (Reoviridae: Sedoreovirinae: Rotavirus: Rotavirus A) virus-like particles | Zendy

S. A. Cherepushkin | Zendy; Tsibezov Vv | Zendy; Anton Yuzhakov | Zendy; O. E. Latyshev | Zendy; Konstantin P. Alekseev | Zendy; E. G. Altayeva | Zendy; К.М. Хаметова | Zendy; G. K. Vorkunova | Zendy; K. A. Yuzhakova | Zendy; Т. В. Гребенникова | Zendy

Open Access

Synthesis and characterization of human rotavirus A (<i>Reoviridae: Sedoreovirinae: Rotavirus: Rotavirus A</i>) virus-like particles

Author(s) -

S. A. Cherepushkin,

Tsibezov Vv,

Anton Yuzhakov,

O. E. Latyshev,

Konstantin P. Alekseev,

E. G. Altayeva,

К.М. Хаметова,

G. K. Vorkunova,

K. A. Yuzhakova,

Т. В. Гребенникова

Publication year - 2021

Publication title -

problems of virology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.151

H-Index - 15

eISSN - 2411-2097

pISSN - 0507-4088

DOI - 10.36233/0507-4088-27

Subject(s) - rotavirus , virology , biology , virus , recombinant dna , reoviridae , plasmid , virus like particle , genotype , microbiology and biotechnology , gene , genetics

Rotavirus infection is the leading cause of acute gastroenteritis among infants. The development of new vaccines against rotavirus A is urgent because the virus has many genotypes, some of which have regional prevalence. Virus-like particles (VLP) is a promising way to create effective and safe vaccine preparations.The purpose of the study is to develop the technology for the production of VLP, containing VP2, VP4, VP6 and VP7 of viral genotypes prevalent on the territory of the Russian Federation, and to give its molecular genetic and virological characteristics.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research