
BALAYAN PARADOX
Author(s) -
М. И. Михайлов,
E. Yu. Malinnikova,
Karen K. Kyuregyan,
Ilya А. Potemkin,
Н. Д. Алсалих,
Olga V. Isaeva,
Anastasia A. Karlsen,
Vera S. Kichatova,
Andrey D. Polyakov
Publication year - 2019
Publication title -
žurnal mikrobiologii, èpidemiologii i immunobiologii
Language(s) - English
Resource type - Journals
eISSN - 2686-7613
pISSN - 0372-9311
DOI - 10.36233/0372-9311-2019-1-80-85
Subject(s) - epidemiology , transmission (telecommunications) , russian federation , hepatitis e virus , incidence (geometry) , virology , hepatitis e , genotype , medicine , biology , geography , pathology , regional science , gene , biochemistry , physics , electrical engineering , optics , engineering
This article presents the results of a study of the epidemiology of hepatitis E in the Russian Federation. Obtained data explaining the phenomenon, known as the Balayan paradox — the wide distribution of anamnestic antibodies to the hepatitis E virus in the absence of a registered incidence. It was shown that imported cases of infection are not able to support the epidemiological process of hepatitis E in Russia. The most cases of HEV infection are autochthonous in nature and are associated with zoonotic transmission of genotype 3 virus from pigs.