Open AccessBACTERIAL ISOLATES AND ANTIBIOTIC SENSITIVITY PATTERNS IN CHOLEDOCHAL BILE COLLECTED DURING ERCP: A REPORT FROM CENTRAL INDIA.
Author(s) -
Mohd Talha Noor,
Vishal Goyal,
Praveen Vasepalli,
Mayank Jain,
Bhagwan Singh Thakur,
Nishat Gorie
Publication year - 2021
Publication title -
paripex indian journal of research
Language(s) - English
DOI - 10.36106/paripex/9606435
Subject(s) - antibiotic sensitivity , antibiotics , imipenem , gastroenterology , medicine , microbiological culture , pseudomonas aeruginosa , microbiology and biotechnology , biliary tract , bacteria , antibiotic resistance , biology , genetics
Temporal shifts have been known to occur in antibiotic sensitivity patterns of organisms causing cholangitis.The aim ofthis prospective study conducted on 100 patients of extra hepatic biliary obstruction (EHBO) was to identify the commonmicroorganisms cultured from bile obtained during Endoscopic retrograde cholangiography and to study their localsensitivity pattern.Sixty six patients had growth in bile culture,the maximum growths amongst all micro-organisms wereof Escherichia coli (40.9%) and Pseudomonas aeruginosa (40.9%). Growth rates were significantly higher in patientswith non- malignant causes of biliary obstruction than those with malignant causes. Polymixins had the highestsensitivity to cultured bacteria followed by aminoglycosides and Imipenem.Study of culture & sensitivity pattern helpsin deciding empirical antibiotic therapy in patients with cholangitis and it should be based on local sensitivity patterns