Open AccessUNDERSTANDING THE METABOLIC RISK FACTOR CLUSTERING: ITS ASSOCIATION WITH OXIDATIVE STRESS AND DIABETES MELLITUS
Author(s) -
Asema Mahveen,
Mir Yousuf Ali,
Asiya Farheen
Publication year - 2021
Publication title -
paripex indian journal of research
Language(s) - English
DOI - 10.36106/paripex/9113438
Subject(s) - oxidative stress , diabetes mellitus , insulin resistance , risk factor , medicine , etiology , bioinformatics , biology , endocrinology
Metabolic risk factor clustering is the key concept of Insulin resistance and Diabetes Mellitus. Oxidative stress plays animportant role in the progression of clustering in the cascade pattern. According to W.H.O. Type 2 Diabetes Mellitus hasalready reached epidemic proportions currently affecting over 422 million people worldwide and one of the fourleading non-communicable diseases highlighted in the targets of the WHO Global Monitoring Framework (2019-20).Oxidative stress from oxidative metabolism had been reported to cause base damage, as well as break strand ingenetic level .oxidative stress is thought to be involved in the development of atherosclerosis (CVD) and had beencited to be of etiological importance in cardiovascular diseases. The present study highlights the various traits ofmetabolic clustering and its association with reactive oxygen species (ROS).