Open AccessA RETROSPECTIVE CROSS SECTIONAL STUDY ON PATTERN & DISTRIBUTION OF PEDIATRIC HEMATOLOGICAL MALIGNANCIES IN CENTRAL PART OF INDIA
Author(s) -
Bimla Banjare,
Amit Kumar Bhardwaj,
Riti Sharma
Publication year - 2020
Publication title -
paripex indian journal of research
Language(s) - English
DOI - 10.36106/paripex/8601226
Subject(s) - medicine , retrospective cohort study , lymphoma , bone marrow , leukemia , population , acute leukemia , pediatrics , environmental health
Hematological Malignancies (HMs) consists of a diverse group of neoplastic diseases involving Bone Marrow, Lymph nodes or other Secondary Immune Organs. Conventionally, HMs represents 2 major group of diseases – Leukemia & Lymphoma. All Hematological Malignancies are on the rise as compared to few decades back worldwide but, it’s major brunt is faced by the under developed countries of the world. A retrospective study in a Government Teaching Hospital was undertaken to characterize Pattern and Distribution of HMs in children in Chhattisgarh state of India. A total number of 65 Bone Marrow Aspiration Cytology cases were evaluated from 1st January 2019 to 31st December 2019 for a period of 1 year. Pediatric Population was categorized into 3 age groups – 0-2 years, 2-12 years and 12-16 years. Male to Female ratio was 2.4:1 in our study with most cases being of Acute Leukemias (95.4%). On further evaluation, ALL had highest numbers with 37 cases (57.0 %) followed by Acute Leukemia and AML with 14 (21.52%) & 10 (15.38%) cases respectively. The highest number of cases were seen in 2-12 years age group (n=49, 75.4%) implying that children of such age group presenting with signs and symptoms of HMs must be thoroughly evaluated for early diagnosis and treatment.