Open AccessA PROSPECTIVE INTERVENTIONAL STUDY COMPARING THE EFFICACY OF FRACTIONAL CO2 LASER AND MICRONEEDLING COMBINED WITH AUTOLOGOUS PLATELET RICH PLASMA IN MANAGEMENT OF STRIAE DISTENSAE
Author(s) -
Sanjay Meena,
Ashok Meherda,
Rajkumar Kothiwala,
Kapil Vyas
Publication year - 2021
Publication title -
paripex indian journal of research
Language(s) - English
DOI - 10.36106/paripex/8204561
Subject(s) - medicine , platelet rich plasma , surgery , patient satisfaction , randomized controlled trial , prospective cohort study , visual analogue scale , platelet
Background:Striae distensae is a very common condition with irregularly linear, several centimetres long. There arenumerous therapeutic modalities available with variable efficacy but none are proven treatment. A Aim and objectives:comparative study of Fractional CO2 Laser Versus Microneedling With Autologous platelet Rich Plasma in striaedistensae. This study was conducted from november 2016–2017 and included 52 patients of striae dist Methods: ensaewhere Group-1 of striae treated by microneedling with autologous PRP and Group-2 treated with Fractional CO2 laser.Randomized prospective study was conducted for a period of 16 weeks. Clinical photographs were taken immediatelybefore and 4 weeks after fourth treatment and VAS score and patient satisfaction score was obtained at the baseline andat the end of 20 weeks to see treatment response. As per the VAS system, mean VAS in the patients Gr Results: oup-1treated by microneedling with prp was 0.8462± 0.3397 at 4 weeks, which later increased to 2.577± 0.6737 at 20th weeki.e. 4 weeks after the last sitting. Mean VAS in patients Group-2 treated by Fractional co2 laser was 1.077±0.3374 at 4weeks, which later increased to 3.077±0.7706 at 20th week i.e. 4 weeks after the last sitting.The difference in mean VAS at4th week between two groups was statistically significant with a p-value of <0.05(0.0110). The difference in mean VAS at20thth week between two groups was statistically significant with a p-value of <0.05(0.0100). Both groups of the patientsshowed statistically significant improvement in striae distensae at the end of 20th weeks however Fractional CO2 laserversus microneedling with autologous PRP was more efficacious in decreasing the extent of striae distensae.Conclusion:Study concluded microneedling with Autologous PRP, and Fractional CO2 Laser both can serve as a safeand efficient treatment in cases of striae distensae but fractional CO2 laser more efficaceous.