Open AccessCOMPARISON OF POST-CONTRAST 3D-T1-SPACE, 3D-T2-FLAIR AND 3D-T1-MPRAGE MR SEQUENCES IN THE EVALUATION OF MENINGEAL AND BRAIN PARENCHYMAL PATHOLOGIES
Author(s) -
Aneeb Mohideen,
V. Dheebha,
S.Harish Priya
Publication year - 2021
Publication title -
paripex indian journal of research
Language(s) - English
DOI - 10.36106/paripex/6409931
Subject(s) - fluid attenuated inversion recovery , medicine , magnetic resonance imaging , contrast (vision) , gradient echo , radiology , nuclear medicine , artificial intelligence , computer science
Background and purpose: The purpose of this study was to assess the value added by contrast-enhanced threedimensional (3D) -T2 fluid-attenuated inversion recovery sequence (FLAIR) and 3D-T1 sampling perfection withapplication optimized contrast using different flip-angle evolutions(SPACE) sequences to conventional post-contrast3D-T1 magnetisation prepared rapid gradient-echo (MPRAGE) images in the evaluation of meningeal and brainparenchymal diseases.Materials and methods:A total of 60 patients with magnetic resonance imaging (MRI) findings suggestive of infectious/ inflammatory / metastatic parenchymal and/or meningeal abnormalities, were selected from patients who underwentMRI brain with intravenous (IV) contrast from March 2019 to Nov 2019.All the patients had their diagnosis confirmed byhistopathological or microbiological studies, as deemed appropriate. Two radiologists independently assessed thepresence of additional information on post-contrast (PC) 3D-T2-FLAIR and 3D-T1-SPACE images and compared themwith PC 3D-T1-MPRAGE images.Results: Both reviewers found that post contrast 3 D-T1-SPACE provided more additional information than post contrast3D-T1-MPRAGE in the evaluation of brain parenchymal and supratentorial meningeal abnormalities.PC 3D-T2-FLAIR isan excellent tool in the evaluation of intratentorial leptomeningeal abnormalities and identifying the scolex in patientswith neurocysticercosis (NCC), presenting with ring enhancing lesions.