Open AccessSTEPS IN THE PROCESS OF NEW DRUG DEVELOPMENT
Author(s) -
Bandaru Hemanth Kumar,
Shaik Farooq Ahmed,
D Prasanthi
Publication year - 2021
Publication title -
paripex indian journal of research
Language(s) - English
DOI - 10.36106/paripex/5306998
Subject(s) - drug discovery , clinical trial , drug development , drug , process (computing) , medicine , identification (biology) , computer science , biochemical engineering , risk analysis (engineering) , pharmacology , intensive care medicine , bioinformatics , engineering , biology , botany , operating system
This review determines the various stages of drug discovery, pre clinical trials and clinical trials. This process involvesthe identification of chemical compound, synthesis, characterization, validation, optimization, screening and assay fortherapeutic efficacy. Once a new drug target or promising molecule has been identified the process of moving from thescience laboratory to the pre clinical to clinical trials have been discussed in this article. The main aim of this process isidentifying the chemical compound which is therapeutically useful in treating and curing the disease. The most commonsteps in the development of a new drug are discovery or synthesis of a potential new drug compound or elucidation of anew drug. Once a chemical compound has shown its therapeutic efficacy in these investigations, it will initiate theprocess of drug development earlier to clinical trials. The drug development from initial idea to the market is a verycomplex process which can take upto 5 to 10 years and cost of $17 billion. Due to high budget of research & developmentand clinical trials drug discovery process is the most expensive. The average time taken for the drug discovery is almost12 -15 years to develop a single new compound and enter into market