Open AccessA STUDY OF CORRELATION OF PAP SMEAR AND COLOPOSCOPY WITH HISTOPATHOLOGICAL FINDINGS IN CASES OF UNHEALTHY CERVIX
Author(s) -
S G Lavanya,
S. Sakthim adhubala,
Gali Niroosha
Publication year - 2021
Publication title -
global journal for research analysis
Language(s) - English
DOI - 10.36106/paripex/4507625
Subject(s) - colposcopy , medicine , cervix , histopathology , gynecology , obstetrics , cytology , predictive value , cervical cancer , biopsy , malignancy , prospective cohort study , radiology , cancer , pathology
BACKGROUND: Cervical malignancy is the second most common among the malignancies in females, with breastcarcinoma the first. Screening of unhealthy cervix by pap smear and supported by colposcopy and histopathology caneasily identify the premalignant lesions and also other non-invasive inflammatory lesions of the cervix.OBJECTIVES: To correlate Pap smear and Colposcopy findings with histopathological findings in detectingpremalignant lesions in the unhealthy cervix.MATERIALS AND METHODS:A prospective observational study was conducted on 100 symptomatic, sexually activewomen of 20-60 years. Pap smears and colposcopy was done for all 100 women who came with complaints of whitedischarge per vagina, intermenstrual, postcoital, or postmenopausal bleeding. The final correlation of the Pap smearand colposcopy was based on histopathology reports.RESULTS: In the present study, the sensitivity of Pap smear for detecting lesions above LSIL was 82.3%, specificity96.9%, PPV was 93.3%, negative predictive value 91.4% and accuracy of Pap smear was 92%. The sensitivity ofcolposcopy in the detection of low-grade lesions and above came out to be 94.1%,specificity 87.8%,positive predictivevalue 80%,negative predictive value 96% and accuracy of colposcopy was 90%.CONCLUSION: This study suggests that the accuracy of detection of cervical abnormalities is higher when cytology,colposcopic guided cervical biopsy and colposcopy are used complimentarily in the diagnosis of cervical lesions.Colposcopy abolishes the need for repeated follow-up as in Pap smear and helps to reduce false-negative cases.