Open AccessA BONE MARROW ASPIRATION STUDY IN FEMALES: A RETROSPECTIVE CASE STUDY AT RIMS RANCHI
Author(s) -
Jayashree Maity,
Rabesh Kumar Singh,
Nasrin Parwin,
Sujit Kumar Murmu
Publication year - 2021
Publication title -
paripex indian journal of research
Language(s) - English
DOI - 10.36106/paripex/3500359
Subject(s) - medicine , etiology , megaloblastic anemia , bone marrow , retrospective cohort study , incidence (geometry) , acute leukemia , microcytic anemia , anemia , pathology , cytology , bone marrow examination , hyperplasia , gastroenterology , pediatrics , leukemia , physics , optics
Background: Bone marrow aspiration (BMA) cytology is a common and cheap technique which reveals the marrowcellularity,its structure,and stages of differentiation of different blood cells.Objectives:The objectives of the study wereto study the incidence , etiology and the common presentation in patients undergoing BMA with special focus on thefemales.Materials and Methods: This is a retrospective study that was carried out in the Department of Pathology ofRIMS Ranchi, India. The study was done from January 20121 -September 2021 on 292cases . BMA was carried out andrelevant clinical history,physical examination, and laboratory data were retrieved. Results: Out of 292 cases, 14 caseswere excluded from the final analysis due to inadequate marrow. Male-to-female ratio was 1.24:1 The most commonindication was unexplained anemia and bleeding.The most common etiological diagnosis was erythroid hyperplasiaEH (35.6% microcytic EH-22% and megaloblastic EH-13%) followed by acute luekemias(16%). Among adolescents(>11– 20 years)-23% and reproductive age group females -21% where erythroid hyperplasia was the most commoncause followed by acute luekemia. Conclusion: The common hematological disorders prevailing in females areerythroid hyperplasia (microcytic EH and EH with megaloblastic changes) main cause being nutritional anemiafollowed by acute leukemia.