Open AccessCARICA PAPAYA LEAF EXTRACT FOR TREATING THROMBOCYTOPENIA IN DENGUE FEVER- AN EXPERIENCE FROM A TERTIARY CARE CENTRE IN EASTERN PART OF INDIA
Author(s) -
Satish K Prasad,
Sameer Kr. Mehta,
Ankit Poddar
Publication year - 2021
Publication title -
paripex indian journal of research
Language(s) - English
DOI - 10.36106/paripex/3207409
Subject(s) - dengue fever , carica , medicine , incidence (geometry) , population , traditional medicine , immunology , biology , horticulture , physics , environmental health , optics
Background: Dengue fever is the most common arboviral mosquito-borne tropical disease of humans caused by thedengue virus. The incidence has increased many fold in India due to unplanned urbanization and migration ofpopulation to urban areas. Aim -To study if Carica papaya leaf extract will significantly increase the platelet count incases of thrombocytopenia associated with Dengue fever. Materials and Methods- The case control study wasconducted in the Department of Medicine of Tata Main Hospital,Jamshedpur.All participants were randomised into twogroups, study group (n=50) and control group (50); the study group was given papaya leaf extract capsule of 1100 mgthrice daily for five days but the control group did not receive it. The basic supportive treatment of dengue fever wasprovided to both the groups. Results- On the first day,platelet count of study group and control group was (63.68 ± 16.88,3and 57.07 ± 17.46×10 respectively, p value=0.0573). The mean platelet count on Day 2, Day 3, Day 4 of CPC3 3 3administration (mean± S.D) was 80.34 ± 18.54×10 ,104.14 ± 20.42×10 ,135.08 ± 19.91×10 in the case group and 64.48 ±3 3 317.02×10 ,77.02 ± 16.88×10 ,100.70 ± 18.33×10 in the control group respectively.The mean duration of stay in the studygroup was 4.6± 0.67 days and 6.76±1.54 days in the control group (p<0.01). Conclusion- Carica papaya leaves extractcapsules offer a cheap and possibly effective treatment for increasing the platelet count in dengue