Open AccessA COMPARATIVE STUDY TO ASSESS THE EFFICACY OF HYDROXYPROPYLMETHYLCELLULOSE POWDER OVER STEROID SPRAY IN TREATMENT OF ALLERGIC RHINITIS IN THE DEPTT. OF ENT AND HEAD & NECK SURGERY, SILCHAR MEDICAL COLLEGE & HOSPITAL
Author(s) -
Tinku Moni Borah,
Smrity Rupa Borah Dutta
Publication year - 2021
Publication title -
paripex indian journal of research
Language(s) - English
DOI - 10.36106/paripex/2403115
Subject(s) - medicine , nasal spray , sedation , anesthesia , head and neck , nasal discharge , topical steroid , allergy , group b , surgery , nasal administration , immunology
Objective: To assess the efficacy of Hydroxypropylmethylcellulose powder over steroid nasal spray in treatment ofallergic rhinitis.Methods: A prospective study of 60 patients suffering from allergic rhinitis was conducted in the ENT and Head & Necksurgery Department, Silchar medical College and Hospital from April 2018 to August 2018.The study subjects weredivided into two groups A and B. Group A was treated with oral antihistaminic and steroid nasal spray, while group B wastreated with oral antihistaminics and HYDROXYPROPYLMETHYLCELLULOSE powder nasal spray for 4 weeks. Thetreatment outcomes were evaluated after 14 days and 28 days from the beginning of treatment, by assessing relief ofsymptom on a five point scale.Results: There was almost similar score in both the groups ranging between score 3 and 4(i.e., relief of nasal obstructionand sneezing) after 14 days of treatment (62% vs 64%). But after 28 days there was significantly better improvementscore of group B study subjects over group A in score 5 (i.e., complete relief from symptoms (83.3% vs. 66.6% ).In boththe groups, mild sedation at the beginning of the treatment was reported in some patients, which is a well known sideeffect of antihistaminics.Conclusion: The result obtained comparing both the groups indicated high efficacy of hydroxypropylmethylcellulosepowder over steroid nasal spray in the treatment of allergic rhinitis.