DOSIMETRIC COMPARISON OF HEART DOSE WITH 3DCRT VS IMRT IN POST-MASTECTOMY LEFT SIDED CHEST WALL IRRADIATION | Zendy

Anushree Loyal | Zendy; Tapan Kapoor | Zendy; Jyoti Sharma | Zendy

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DOSIMETRIC COMPARISON OF HEART DOSE WITH 3DCRT VS IMRT IN POST-MASTECTOMY LEFT SIDED CHEST WALL IRRADIATION

Author(s) -

Anushree Loyal,

Tapan Kapoor,

Jyoti Sharma

Publication year - 2022

Publication title -

paripex-indian journal of research

Language(s) - English

Resource type - Journals

ISSN - 2250-1991

DOI - 10.36106/paripex/0800341

Subject(s) - medicine , radiation therapy , nuclear medicine , dosimetry , mastectomy , radiology , breast cancer , cancer

Purpose: Data regarding the efficacy of various radiotherapy techniques for post mastectomy chest-wall radiotherapy(PMRT) using hypofractionation is scarce and cardiac toxicity remains a concern.This study aims to compare effect ofIMRT (Intensity Modulated Radiation Therapy) and 3D-CRT (3-Dimensional Conformal Radiation Therapy) techniqueson cardiac dose.Materials and Methods: In this retrospective study,we compared IMRT and 3DCRT plans of 20 patients who receivedPMRT to a dose of 42.56Gy/16# and the dosimetric parameters in terms of planning target volume (PTV) coverage anddose to organ at risk (OARs) including heart and ipsilateral lung were recorded and analyzed.Result: PTV coverage were comparable with both techniques. IMRT planning provided a better conformity index ascompared with 3DCRT (0.95 vs 0.91, p<0.001).The mean dose to the heart significantly reduced with IMRT (4.36Gy vs8.2Gy,p<0.00001).Conclusion: IMRT offers a significant reduction in mean heart dose than 3DCRT in patients treated withhypofractionated post-mastectomy irradiation.

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