Open AccessEVALUATION OF A CORRELATION BETWEEN SLEEP HOURS, SLEEP QUALITY AND SALIVARY LEVELS OF 8-HYDROXY-2'-DEOXYGUANOSINE IN CHRONIC PERIODONTITIS PATIENTS- AN OBSERVATIONAL STUDY
Author(s) -
B Ayswaria,
Mathew John,
Sabari Chandramohan,
Bindu Rachel Thomas,
Aswathy Sreedevi,
Revu Das S D
Publication year - 2020
Publication title -
international journal of scientific research
Language(s) - English
DOI - 10.36106/ijsr/9821615
Subject(s) - pittsburgh sleep quality index , medicine , chronic periodontitis , sleep (system call) , observational study , periodontology , saliva , sleep quality , periodontitis , sleep disorder , dentistry , gastroenterology , physical therapy , insomnia , psychiatry , computer science , operating system
Aims: To determine if there was a correlation between sleep hours, sleep quality with the salivary levels of 8-hydroxy-2’-deoxyguanosine in chronic periodontitis patients, and to decide its relationship with the established clinical periodontal parameters.Settings and Design: Observational analytical study with 100 patients based on the inclusion criteria, who visited the Department of Periodontology of a tertiary care setting. Methods and Material: Bleeding on probing, pocket depth, clinical attachment loss, plaque index score were recorded. Sleep behaviour longer than a month time stretch was surveyed by Pittsburgh Sleep Quality Index, a validated questionnaire. 8-OHdG levels in un-stimulated saliva of all subjects were examined by ELISA.Statistical analysis used: Sleep-hour correlations with sleep quality at salivary 8-OHdG levels as well as clinical periodontal parameters were assessed using the Pearson correlation coefficient. All statistical analysis was performed using SPSS software version 17.0.Results: Salivary 8-OHdG levels and clinical parameters (PPD, CAL, PI) were significantly higher among sleep deprived individuals. On comparison, subjects with a poor quality of sleep (PSQI score>5) showed a significantly higher 8-OHdG levels.Conclusions: Short sleep durations and poor sleep quality can instigate inflammation and oxidative stress and could be a risk factor for periodontitis.