A PROSPECTIVE STUDY ON PIOGLITAZONE EFFECT IN REDUCING TRIGLYCERIDE LEVEL IN TYPE-2 DIABETIC PATIENTS

Type 2 diabetes mellitus is the most common form of diabetes mellitus characterized by hyperglycemia, insulin resistance, and relative insulin deficiency Dyslipidemia being common with diabetes, if we have a drug which can take care of both diabetes and Dyslipidemia, it will be more economical as well as increases the patient compliance. There are many studies on the effect of pioglitazone on triglyceride level. So this study was an attempt to find the effect of pioglitazone in diabetic patients with dyslipidemia in rural population. History taking and investigations were taken in 30 out patients visiting government sivagangai medical hospital between May 2019 and June 2019 The pre-treatment FBS mean was found to be 149.4+41.5 and the post treatment mean was found to be 98.2+27.3. Thus there is a significant reduction in fasting blood sugar level with p value less than 0.05. Serum triglycerides investigation pre treatment mean was found to be 181.5+18.2 and the post treatment mean is 160.07+21.03 .Thus there is a significant decrease of p<0.05 when pre and post treatment mean values were compared. The effect of pioglitazone on triglyceride level in type 2 diabetic patients was studied, it is evident that the Pioglitazone is both antidiabetic and antiatherogenic drug; we can conclude that the pioglitazone administration is effective to bring about significant change in the blood sugar, triglycerides. pioglitazone is a safe drug with less of side effects. , it will be more economical as well as increase patient compliance.