CONCEPT OF AUTOIMMUNE HEPATITIS IN AYURVEDA PERSPECTIVE – A CONCEPTUAL STUDY

Autoimmune hepatitis is a chronic inammatory disorder characterized by high levels of aminotransferase and auto antibodies,hypergammaglobulinemia and interface hepatitis. The etiology of AIH has not been completely elucidated, but immunogenetic background andenvironmental parameters may contribute to itsdevelopment. Autoimmune hepatitis does not have a pathgnomonic features, and itslaboratory,serologic, andhistologic manifestations are found in acute and chronic liver disease of diverse causes.Autoimmune Hepatitis can becompared to mandya Bhutangni in Yakrit. According to Ayurveda,Yakrut is the main site of Bhutangni and one of the sub types of pitta namelyRanjakapitta. This Bhutangni helps in the digestion process as well as Ranjakapitta imparts colour to the blood. According to Charkathe digestionof food by jatharangi results in the breakdown of food in to ve distinct physiochemical groups. Jatharangi ignites the Agni fraction present in eachof ve groups. This Bhutangni then converts the respective portion in to assimilable form. If the function of Bhutangni is not proper, at this stageAma would be produced is called Bhutangni Manda janya Ama. If Agni improperly processed during digestion and metabolism of food it disturbsthe process leading formation of Ama. Which is responsible for the manifestation of almost all disease especially autoimmune hepatitis comparedwith Bhutangni giving a detailed literature overview of Bhutangni, Immunopathogenesis (Ama production) and diagnostic criteria.