Open AccessSEVERE IMMUNE THROMBOCYTOPENIA IN A PATIENT WITH HIV-HCV COINFECTION
Author(s) -
R. Murugaraj,
V. Padma,
Rameez Raja
Publication year - 2020
Publication title -
international journal of scientific research
Language(s) - English
DOI - 10.36106/ijsr/3134245
Subject(s) - coinfection , medicine , immune thrombocytopenia , immunology , human immunodeficiency virus (hiv) , immune system , platelet , etiology , hepatitis c virus , cirrhosis , virus
Thrombocytopenia in a patient with HCV – HIV co-infection can hav e a multitude of causes. Thrombocytopenia is seen in 5-30% of HIV patients.1 The most common cause of thrombocytopenia in HIV patients is HIV-associated thrombocytopenia. The aetiology for HIV associated thrombocytopenia is complex and is due to both immune mediated peripheral destruction of platelets as well is reduced platelet production from the progenitor cells. However secondary causes of thrombocytopenia needs to be ruled out in all patients with HIV infection. Common secondary causes for thrombocytopenia include infections (viral, bacterial, fungal and parasitic), malignancies, drugs, hypersplenism and other causes of cirrhosis. In our patient no secondary cause could be found except for co- infection with Hepatitis C virus.