Open AccessEFFICACY OF CORNEAL COLLAGEN CROSSLINKING WITH RIBOFLAVIN AND ULTRAVIOLET-A IN PROGRESSIVE KERATOCONUS.
Author(s) -
Priyanka Raut,
Nikhilesh Wairagade,
Praneeta Sakarkar
Publication year - 2020
Publication title -
international journal of scientific research
Language(s) - English
DOI - 10.36106/ijsr/3021115
Subject(s) - keratoconus , keratometer , corneal collagen cross linking , ophthalmology , medicine , riboflavin , ethics committee , visual acuity , prospective cohort study , cornea , surgery , chemistry , biochemistry , public administration , political science
PURPOSE-To evaluate outcomes of collagen crosslinking in patients having progressive keratoconus.METHODS- A prospective study was done in eyes that underwent corneal collagen crosslinking for treatment of progressive keratoconus. Thisstudy was performed after approval from Institutional Ethics Committee and informed consent was obtained from all the patients. Data wasanalysed with the help of JASP0.8.3.1 and MS-Excel 2013.RESULT-The mean age was 20.94 ± 2.04 years. 21 (63.63%) were males, 12 (36.36 %) were females. The mean uncorrected visual acuity (UCVA)pre-operative and post-operative at 6 months were 0.64 ± 0.37 and 0.53 ± 0.31 (logMAR) respectively (p value 0.03). Mean spherical equivalentpre-operatively and post-operatively at 6 months were -2.85 ± 2.14 and -2.38 ± 1.70 respectively (p < 0.001). Mean keratometry (Mean K) preoperative and post-operative were 49.85 ± 4.10 Dioptres (D) and 49.22 ± 4.09 D respectively (p = 0.0007).CONCLUSION- Corneal collagen crosslinking with UV-A and riboavin is a safe and effective method for halting the deterioration ofprogressive keratoconus.