Open AccessSURVIVALAND PROGNOSTIC FACTORS FOR GLIOBLASTOMA MULTIFORME: A RETROSPECTIVE SINGLE INSTITUTIONAL STUDY
Author(s) -
Maneet Gill,
Chinmaya Srivastava,
Sudhanshu Agarwal,
Lokesh Gautam
Publication year - 2020
Publication title -
international journal of scientific research
Language(s) - English
DOI - 10.36106/ijsr/2722285
Subject(s) - medicine , glioblastoma , retrospective cohort study , overall survival , cohort , surgery , survival analysis , oncology , cancer research
OBJECTIVEThe purpose of the present retrospective analysis was to present and discuss clinical features (Patient specific and tumour specific) and various prognostic factors that predict the survival of the patients with Glioblastoma multiforme (GBM) and to compare the results with pre-existing literature. MATERIALS &METHODSA single institutional data of 221 patients of GBM was reviewed from 2014 to 2018. Data regarding patients’ factor,tumour factor and survival analysis were collected and based on the above factor’s survival outcome was calculated.RESULTSA total of 221 patients were analysed. 197 patients underwent resection and 24 patients underwent biopsy (Open or stereotactic). Patients had a mean age of 56.5 years at the time of diagnosis. Median survival in patients 50 years was 4.56 months. The overall survival was 4.27% for the entire cohort at the end of two years. CONCLUSIONIn patients with GBM overall survival and prognosis remains dismal.Standard treatment includes resection followed bychemo-radiation which has improved the overall survivaloutcome. However, the prognosis continues to remains poor.