Open AccessTUCK IN CONJUNCTIVALAUTOGRAFTING WITH IN SITU LIMBAL STEM CELL TRANSPLANTATION IN CASE OF RECURRENT PTERYGIUM IN CENTRAL INDIA
Author(s) -
Shweta Kumari,
M. Mazen Jamal
Publication year - 2020
Publication title -
international journal of scientific research
Language(s) - English
DOI - 10.36106/ijsr/2030456
Subject(s) - medicine , pterygium , surgery , transplantation , limbal stem cell , stem cell , fibrin glue , ophthalmology , cornea , corneal epithelium , genetics , biology
AIM: To report outcome and recurrence with Tuck in conjunctival autografting with in situ limbal stem cell transplantation in case of recurrent pterygium in central India where cost is a limiting factor in use of any sutures, Amniotic membrane, Fibrin glue, Mitomycin or Avastin. METHODS: A randomized, non-comparative interventional and prospective clinical study was carried out on 50 patients of recurrent nasal and temporal pterygium at MGM Medical college and Hospital, Jamshedpur from August 2019 to September 2020. Patients with cystic atrophic and Inflamed pterygium, pseudo pterygium, other ocular disorders like Sjogren’s syndrome, blood clotting disorders, glaucoma medication, stents or filtering bleb were excluded from the study. RESULTS: Mean age was32.2 years. Mean follow up was 12.2 months. Outcome measures were cosmetic satisfaction, recurrence rate, graft edema, graft dislocation, graft failure and loss of graft. CONCLUSION: Pterygium being a local limbal stem cell deficiency , its surgical treatment by replenishment of limbal stem cells by tuck in conjunctival autografting with in situ limbal stem cell transplantation is a viable option In cases of recurrent pterygium and is a cheap alternative alleviating need of any sutures, tissue adhesive , antimitotic drugs ,anti VEGFS ,with a lesser intraoperative time, excellent cosmetic result and low recurrence rate.