Open AccessA CASE REPORT ON IMPACT OF PRE-GESTATIONAL DIABETES MELLITUS ON PREGNANCY OUTCOME IN A WOMEN WITH BAD OBSTETRIC HISTORY
Author(s) -
Ayushi N Vazirani,
Vidhya Selvam
Publication year - 2021
Publication title -
international journal of scientific research
Language(s) - English
DOI - 10.36106/ijsr/0500164
Subject(s) - medicine , abortion , obstetrics , pregnancy , gestational diabetes , glycemic , intrauterine growth restriction , diabetes mellitus , fetus , gestation , endocrinology , genetics , biology
BackgroundPerinatal and neonatal mortality remains a challenge in the care of pregnant women worldwide, particularly for those who had a history of adverse outcome in previous pregnancies.Bad Obstetric History implies previous unfavorable fetal outcome in terms of two or more consecutive spontaneous abortion, H/O intrauterine fetal death, intrauterine growth restriction, stillbirth, early neonatal death and/or congenital anomalies. Age, obesity and high parity have been shown to be independent risk factors for recurrent pregnancy loss and stillbirths. About 3 to 10% of pregnancies are complicated by glycemic control abnormalities. The main underlying cause is lethal embryonic malformations due to glucose teratogenicity at high levels if diabetes is poorly controlled in the periconceptional period and first trimester.