Open AccessMATERNALAND PERINATAL OUTCOME IN PREECLAMPSIAAND ECLAMPSIA IN RELATION TO LDH LEVELS
Author(s) -
Priti Singh,
Krishna Sinha
Publication year - 2020
Publication title -
indian journal of applied research
Language(s) - English
DOI - 10.36106/ijar/7211164
Subject(s) - eclampsia , medicine , lactate dehydrogenase , preeclampsia , obstetrics , pregnancy , placental abruption , gynecology , fetus , enzyme , biology , biochemistry , genetics
Lactate Dehydrogenase (LDH) is an intracellular enzyme. Recently LDH has been suggested as potential marker to predict severity of pre- eclampsia. The aim of present study was to correlate LDH levels in pregnant women and women with Preeclampsia and eclampsia in antepartum period and to correlate maternal and perinatal outcomes with LDH levels. Pregnant women in this study were enrolled in 3rd. trimester from 28 weeks onwards . Case control study was done in 100 women with normal B.P and in another 100 women having Pre-eclampsia and Eclampsia. Serum LDH levels were measured in all women and maternal and perinatal outcome was assessed. A significant positive correlation was found in patients with Pre-eclampsia and Eclampsia . LDH levels gradually increased with increase in the severity of the disease.Regular monitoring of serum LDH levels in such patients may help in detecting severity of the disease and associated end organ damage.The maternal complications were found to be maximum in women with LDH > 800 IU/l. Abruption was the most common complication.