Open AccessCORRELATION OF NEUTROPHILLYMPHOCYTE RATIO WITH GLYCOSYLATED HB IN PATIENTS WITH TYPE 2 DIABETES MELLITUS.
Author(s) -
V Sandeep Kumar,
Adrish Anand
Publication year - 2020
Publication title -
indian journal of applied research
Language(s) - English
DOI - 10.36106/ijar/2609391
Subject(s) - medicine , diabetes mellitus , leukocytosis , type 2 diabetes mellitus , white blood cell , neutrophil to lymphocyte ratio , gastroenterology , lymphocyte , absolute neutrophil count , glycosylated haemoglobin , immunology , type 2 diabetes , endocrinology , toxicity , neutropenia
Neutrophilic leukocytosis is directly associated with the pathogenesis of atherosclerosis in patients with diabetes mellitus (DM). Increased white blood cell (WBC) count is related to cardiovascular disease in patients with type 2 diabetes mellitus; raised neutrophil lymphocyte ratio (NLR) is associated with metabolic syndrome. concerning a correlation between glycosylated haemoglobin (HbA1c) and NLR. Aims and objectives: The aim of the present study was to investigate the neutrophils lymphocyte ratio (NLR) and blood glucose regulation in type 2 diabetes patients. Methods: This prospective study of 6 months duration was conducted in patients with type 2 diabetes mellitus, divided into two groups according to HbA1c levels. group 1- HbA1c levels ≤ 7%; group 2-HbA1c levels > 7%. WBC, neutrophil and lymphocyte counts were determined by automated analyser, HbA1C was calculated using Afinion 2.Results: Of total 50 patients included, Random blood glucose, neutrophil , WBC counts ,NLR, HbA1C were significantly higher in group 2 compared to group 1.Conclusion:NLR of uncontrolled group (HbA1c>7%)was significantly higher than that of controlled group(HbA1C<7%) .We conclude that NLR gives us very good and similar results to know the early complications of uncontrolled DM.