Open AccessSTUDY OF PLATELET VOLUME INDICES IN PATIENTS OF CORONARY ARTERY DISEASE
Author(s) -
Bhatt Payal,
Joshi Mauli,
Inaniya Kailash,
Sanjay Chaudhari
Publication year - 2021
Publication title -
global journal for research analysis
Language(s) - English
DOI - 10.36106/gjra/6700407
Subject(s) - medicine , cardiology , conventional pci , coronary artery disease , mean platelet volume , percutaneous coronary intervention , disease , artery , myocardial infarction , platelet
Background: Various relations have been found out regarding the role of platelets in thrombosis andcoronary heart disease. This study is an earnest attempt to delineate the relations between the variousplatelet volume indices (PVI) and their role in coronary heart disease. Method: During the study period of April 2014 to March2015, total 180 subjects were studied. Out of them 120 were cases and 60 were controls. The cases of coronary artery diseasewere divided in to two groups A and B, according to their treatment. Group A included 60 patients with acute coronarysyndromes, mainly AMI and UA with medical treatment. Group B included 60 patients with any percutaneous coronaryinterventions (PCI) for previous ischemic event. Group C included 60 healthy individuals from health check-up unit. A brief andrelevant clinical history and laboratory investigations will be taken on the prepared Performa for the subjects. The EDTA andplain samples of 180 subjects were processed in the Central Diagnostic Laboratory. Results: The present study showed higherPVI in the group A and group B when compared to the control group. MPV, PDW and P-LCR were signicantly reduced aftertreatment in both groups A and B. The mortality was more in those with higher PVI. Conclusion: Coronary artery disease isassociated with signicant morbidity and mortality. Platelet volume indices in histograms are easily generated by automatedcell counter. Thus, by assessment of it we can predict an impending coronary event. We can prevent reinfarction by monitoringof it. The risk of acute coronary event is also decreased after treatment.