Open AccessROLE OF VITAMIN D3 LEVELS IN PROGNOSTICATION OF PATIENTS DIAGNOSED OF HODGKIN'S LYMPHOMA: A PROSPECTIVE COHORT STUDY
Author(s) -
Akshay Sharma,
Abhimanyu Patial
Publication year - 2020
Publication title -
global journal for research analysis
Language(s) - English
DOI - 10.36106/gjra/6108193
Subject(s) - medicine , prospective cohort study , interim analysis , cohort , univariate analysis , lymphoma , oncology , stage (stratigraphy) , interim , non hodgkin's lymphoma , chemotherapy , gastroenterology , multivariate analysis , clinical trial , history , paleontology , archaeology , biology
Hodgkin’s lymphoma (HL) constitutes around 30% of all lymphomas(1). IPS is used for the risk stratification of advanced stage HL but it lack applicability to the early stage cases(1)..In this prospective cohort study, we aim to confirm the relationship between vitaminD3 levels with treatment response (interim as well as end of treatment) of HL treated with the standard chemotherapy and radiotherapy regimens. A total of 50 patients were recruited over a period of 18 months and the patients were followed up in the hematology clinic and interim treatment responses as well as end of treatment response were assessed. Correlation of the vitaminD3 levels and the treatment response showed that the low levels of vitaminD3 were associated with more advanced stages. Univariate analysis showed that there was no significant correlation of interim treatment response as well as end of treatment response with vitamin D3 levels.