Open AccessABNORMALITY IN SERUM CALCIUM, PHOSPHATE AND VITAMIN-D LEVELS IN CHRONIC RENAL FAILURE PATIENTS: A CASE CONTROL STUDY IN THE EASTERN INDIAN POPULATION
Author(s) -
Chinmoy Ghosh,
Sandip Chakraborty,
Arnab Ghosh,
Somnath Dasgupta
Publication year - 2021
Publication title -
global journal for research analysis
Language(s) - English
DOI - 10.36106/gjra/1805785
Subject(s) - medicine , creatinine , abnormality , vitamin d and neurology , kidney disease , population , endocrinology , calcium , chronic renal failure , nephrology , vitamin d deficiency , calcium metabolism , gastroenterology , renal function , vitamin , environmental health , psychiatry
Chronic renal failure (CRF) is one of the most important health problems in our population. From the earlystages of the disease progression, the activation of Vitamin D in kidney is affected, resulting inabnormality in the regulation of calcium and phosphate homeostasis in the blood. In the present study, 30 Chronic Renal Failurepatients visiting Nephrology OPD and 30 age and sex matched volunteers were studied. Serum levels of Urea, Creatinine,Calcium, Phosphate and Vitamin D were measured in the study participants. The data after statistical analysis showedsignicantly higher levels of Phophate and signicantly lower levels of Calcium and Vitamin D in the CRF patients incomparison to healthy control subjects. Phosphate and Vitamin D also shows signicant correlation with serum creatinine levelsin the CRF patients. The present study conrms the abnormality in Calcium-Phosphorus metabolism as a complication of CRF inour population, and highlights the importance of regularly measuring these parameters in CRF patients and possible need oftaking corrective measures in this regard.