Open AccessPengaruh Bahan Pengisi Terhadap Massa Cetak Tablet Vitamin C
Author(s) -
Desy Nawangsari
Publication year - 2019
Publication title -
viva medika
Language(s) - English
Resource type - Journals
eISSN - 2656-1034
pISSN - 1979-2026
DOI - 10.35960/vm.v11i02.464
Subject(s) - angle of repose , microcrystalline cellulose , granule (geology) , ascorbic acid , filler (materials) , materials science , chemistry , chromatography , mathematics , composite material , cellulose , food science , organic chemistry
Avicel® PH is branded name from microcrystalline cellulose that is generally used in pharmaceutical preparations. Avicel® PH are being used as filler or binder in dosage formulas in tablets especially for direct compression because having a good flowing rate and a good compressibility. This study aims to compare the influence of the use Avicel® PH 101 and Avicel® PH 102 as a filler on of preparations a tablet of ascorbic acid. A method of the research was conducted by making granule of ascorbic acid tablet with the variation filler, then the granule was evaluate in .The results showed Avicel® PH 102 as a filler produce granule which better seen from the flowability, static angle of repose, carr’s index and hausner ratio .