Open AccessSynthesis, Characterization and Biological Activity Study of New Compounds Tetrazole Derivatives Azo-Schiff Base
Author(s) -
Hiba Ibrahim Abdulla AL-Joubory,
Khalid Mohamad Motny Al-janaby
Publication year - 2019
Publication title -
mağallaẗ kulliyyaẗ al-tarbiyaẗ al-asāsiyyaẗ
Language(s) - English
Resource type - Journals
ISSN - 2706-8536
DOI - 10.35950/cbej.v25i103.4547
Subject(s) - aniline , schiff base , chemistry , benzaldehyde , tetrazole , aldehyde , benzoic acid , organic chemistry , solvent , sodium azide , polymer chemistry , nuclear chemistry , catalysis
This work included synthesis of azo dye (H1) by the reaction of diazonium salt to sulfacetamide with 4-hydroxy benzaldehyde at (0-5) oC and synthesis of schiff base (H2-H6) through reaction substituted aromatic amine (aniline, 4-nitro aniline, 4-chloro aniline, 4-amino benzoic acid and phenyl hydrazine) with aldehyde group in azo compound (H1) in ethanol compounds (H2-H6) and tetrazole derivatives prepared by reaction schiff base with sodium azide in ethanol compounds (H7-H11) and characterization by using spectroscopic techniques Uv/Vis, FT-IR, C.H.N. and H1-NMR of some the prepared compounds using DMSO-d6 a solvent, in addition melting point and determination a purity of TLC, and this work consists a study of biological activity for the some prepared compounds against four types of pathogenic bacteria and know to be resistant to anti biotic.