Evaluation of Bactericidal Activity of Garcinia Gummi-Gutta and Gymnema Sylvestre- A Plant of Ethano Medicinal Importance

Antibiotic defiance in bacterial is a satisfactory obstacle in the latest world. Day-to-day novel dopes are being intact to defeat this drawback. The goal of this is trained used to be to check antimicrobial resistance of the Garcinia gummi-gutta and Gymnema Sylvestre. The dried fruit of G. Gummi-gutta and G.Sylvestre crops are located in a southern state of India. The extract of dried fruit of G. Gummi-gutta and G.Sylvestre leaf was once ready through using specific solvent of Ethyl Acetate. These ready extracts have been used for evaluation of antibacterial ability in opposition to three Gram-positive bacterial stains (Escherichia coli, Salmonella typhi, Pseudomonas aeruginosa) and two gram-negative bacterial stains (Streptococcus, Staphylococcus aureus). The antimicrobial ability was appraised by Disc diffusion assay of G. Gummi-gutta and G.Sylvestre. The zone of inhibition used to be determined at the concentration of (500µg/ml) in G.Gummi-gutta Streptococcus& Pseudomonas aeruginosa (14mm), Staphylococcus aureus& Salmonella typhi (9mm), Escherichia coli (8mm). The zone of inhibition was once determined at the concentration of (500µg/ml) in G.Sylvestre.The Streptococcus(11mm), Staphylococcus aureus& Escherichia coli (9mm), Salmonella typhi(10mm), Pseudomonas aeruginosa (8mm) respectively. Due to the fact, the extract confirmed a wide spectrum of the antimicrobial undertaking of each Gram positive and gram negative bacterial isolates. Comparative reports of the G. Gummi-gutta and G.Sylvestre.The nice one among G.Sylvestre. Can be utilized as a bio preservative or therapeutic agent to prevent a few illnesses.The dried leaves of G.Sylvestre would characterize a novel antimicrobial obtain with steady, adoptive energetic compounds that may prove a scientific base for the consumer in recent treatment.