Open AccessA Simulation Model for Interaction between Cyclic Variation of Brain Tissue Temperature and Intracranial Pressure
Author(s) -
Kavita Goyal,
Moin Uddin,
Vikas Jindal
Publication year - 2019
Publication title -
international journal of innovative technology and exploring engineering
Language(s) - English
Resource type - Journals
ISSN - 2278-3075
DOI - 10.35940/ijitee.a4006.119119
Subject(s) - cerebral blood flow , intracranial pressure , brain tissue , cerebral blood volume , blood flow , middle cerebral artery , blood pressure , medicine , anesthesia , cardiology , biomedical engineering , ischemia
The brain responds with high sensitivity in case of cerebral damage. Brain temperature (BT), cerebral blood flow (CBF), cerebral blood volume (CBV) and intracranial pressure (ICP) are essential parameters for brain revival in case of cerebral damage. For this reason, the coordinated learning of BT, CBF and ICP is required for improving the remedial impacts. Thus, in this exploration, a simulation model has been developed for association between brain tissue temperature (BTT), CBF, CBV and ICP to improve the apprehensions of the ICP. It includes the cardiac output, partial pressures of oxygen and carbon dioxide in cerebral artery and vein, temperature variations of brain tissue, cerebral metabolic process and pressure-volume relationship for cranial cavity. The model simulates the interaction between arterial blood pressure, BTT, produced amount of CO2 from brain tissue, changes in CBV and changes in ICP. The results show that the ICP and CBV will increase with an increase in brain tissue temperature. This model elaborates the physiology of BTT and ICP with less complexity.