Open AccessMicrofluidic Microchannel (Size And Shape) for Single Cell Analysis by Numerical Optimization: Lateral Trapping Method
Author(s) -
M. Sushmitha,
Joshia Issac R A,
Vigneswaran Narayanamurthy,
N Padmasini.,
Fahmi Samsuri
Publication year - 2019
Publication title -
international journal of engineering and advanced technology
Language(s) - English
Resource type - Journals
ISSN - 2249-8958
DOI - 10.35940/ijeat.a1136.1291s419
Subject(s) - multiphysics , microchannel , microfluidics , microelectronics , finite element method , computer science , flow (mathematics) , software , computational fluid dynamics , mechanical engineering , fluid dynamics , mechanics , materials science , nanotechnology , engineering , physics , structural engineering , programming language
The primary objective of this work is to show simulation outputs from the developed model of cell flow within a microfluidic device. This work is essential because it requires computational models to offer compact sized biomedical equipment that involves microfluidics technology. Microfluidics has become a common technology for life science applications in latest years. The purpose is to learn the effect of various microchannel size and shape with lateral traps for single cell analysis and to arrive at an optimum design based on a simulation study using COMSOL Multiphysics software. Thus in order to develop software model of various microchannels which execute fluid flow in the microelectronic device. This research provides numerical alternatives from finite element analysis simulation using the software COMSOL-Multiphysics to characterize the shape and size of the microchannel initializing the fluid flow. Optimized design analysis and operating conditions for efficient single cell trap is reported.