Open AccessStudy of Antidote Activity of Zinc Ascorbate in Acute Mercury Lesions
Publication year - 2017
Publication title -
vestnik vojsk rhb zaŝity
Language(s) - English
Resource type - Journals
ISSN - 2587-5728
DOI - 10.35825/2587-5728-2017-1-2-14-23
Subject(s) - antidote , zinc , mercury (programming language) , ascorbic acid , chemistry , lesion , pharmacology , biochemistry , medicine , pathology , toxicity , food science , organic chemistry , computer science , programming language
The article is dedicated to the study on the antidote activity of zinc ascorbate (С 6 Н 8 О 4 Zn) in acute mercury lesions. Biologically active zinc-containing substance – zinc ascorbate – is synthesized. It is determined that in case of acute mercury lesions the survival rates are much higher (from 10 to 67 %) for those experimental animals, which preliminarily have been treated with the therapeutic doses of zinc ascorbate, and their peripheral blood parameters (the percentage of dead leukocytes, the content of toxic granules in leukocytes, sulfhydryl groups in leukocytes and free sulfhydryl groups in blood serum) are close to the physiological norm. These data show that zync salt of ascorbic acid definitely can protect from toxic effects of mercury and can be used as a prophylactic antidote in case of the subsequent acute mercury lesion