Open AccessNonsecretory Multiple Myeloma in a Seropositive Hepatitis B Patient with Thrombocytosis: A Case Report
Author(s) -
Muhammad Ali Fayyaz
Publication year - 2021
Publication title -
journal of islamabad medical and dental college
Language(s) - English
Resource type - Journals
eISSN - 2707-0484
pISSN - 2227-3875
DOI - 10.35787/jimdc.v10i2.632
Subject(s) - multiple myeloma , medicine , serum protein electrophoresis , thrombocytosis , myeloma protein , bence jones protein , dyscrasia , bone marrow , anemia , pathology , gastroenterology , immunoglobulin light chain , immunology , monoclonal , antibody , monoclonal antibody , plasma cell , platelet
Non-secretory Multiple Myeloma is a rare variant of multiple myeloma with similar clinical and radiological findings. It is characterized by the absence/lack of monoclonal M proteins in the serum and/or urine. An early diagnosis can help in alleviating its adverse outcomes. We report a case of a 56-year-old female presenting with generalized body weakness and swelling, pain in right lower chest and anorexia. The patient was a known case of hepatitis B, treated a month ago. There was an incidental finding of thrombocytosis. Serum biochemistry and protein electrophoresis showed no findings in favor of Multiple Myeloma. Bence Jones proteins were negative in the urine. X-ray revealed few lytic lesions on calvaria of the skull. Bone marrow biopsy helped in diagnosing the patient as a case of non-secretory type of multiple myeloma highlighting the important role of this modality in saving the life of a patient through early diagnosis.