Open AccessCORRECTION OF LIPID AND HEMOSTATIC DISORDERS IN PATIENTS AT HIGH RISK OF CARDIOVASCULAR DEATH
Author(s) -
О. А. Рубаненко,
О. А. Рубаненко,
Н. А. Кириченко,
Н. А. Кириченко,
О В Фатенков,
О В Фатенков
Publication year - 2016
Publication title -
nauka i innovacii v medicine
Language(s) - English
Resource type - Journals
eISSN - 2618-754X
pISSN - 2500-1388
DOI - 10.35693/2500-1388-2016-0-1-41-45
Subject(s) - rosuvastatin , atorvastatin , medicine , gastroenterology , lipid profile , coagulation , cholesterol
Aim - to study the peculiarities of lipid and coagulation abnormalities in high risk patients, and also the possibilities of their correction with statin therapy. Methods. 102 patients were studied, 1 group included patients with LDL 3.0-3.9 mmol/l (n=59), who received atorvastatin 40 mg daily with titration to 80 mg daily, 2 group - patients with LDL >4.0 mmol/l (n=48), who received rosuvastatin 10 mg daily with titration to 20 mg daily. Results. In the 1 group of patients, after 24 weeks mean LDL level decreased by 43.3% (p