Open AccessSynthesis and characterization of Fe(III) complex with thiosemicarbazide-based ligand
Author(s) -
Semira Galijašević
Publication year - 2020
Publication title -
glasnik hemičara i tehnologa bosne i hercegovine
Language(s) - English
Resource type - Journals
eISSN - 2232-7266
pISSN - 0367-4444
DOI - 10.35666/ghtbh.2020.55.03
Subject(s) - salicylaldehyde , deprotonation , chemistry , ligand (biochemistry) , semicarbazone , medicinal chemistry , metal , condensation reaction , thiol , stoichiometry , stereochemistry , organic chemistry , schiff base , catalysis , receptor , ion , biochemistry
Complex iron(III) salicylaldehyde thiosemicarbazone with a formula Na[Fe(STSC)2] have been synthesized. Ligand, salicylaldehyde thiosemicarbazone (SCT) was prepared through the condensation reaction of salycilaldehide with thiosemicarbazide. Na[Fe(STSC)2] has been synthesized by reacting FeCl3 with thiosemicarbazide based ligand bearing ONS donor atoms. Complex has been formulated and characterized by mass spectrometry, infrared and UV/visible spectroscopy. The facts showed the formation of a complex in metal:ligand stoichiometric ratio 1:2. The ligand is coordinated as an ONS tridentate dianion via oxygen atom after the deprotonation of the phenolic OH-group, azomethine nitrogen and sulphur in thiol form of the deprotonated thiosemicarbazide residue. Antioxidant activity was determined, where ligand showed significant activity, while complex, at low concentration, exhibited almost no activity.