Open AccessCRYSTALLOSCOPIC MONITORING OF THE EFFECTIVENESS OF SYSTEMIC RETINOIDS IN PATIENTS WITH SEVERE ACNE
Author(s) -
Polina Krivonogova,
А. К. Мартусевич,
Oksana Bitkina,
Lida K. Kovaleva,
Alexandra Surovegina
Publication year - 2022
Publication title -
archiv euromedica
Language(s) - English
Resource type - Journals
eISSN - 2199-885X
pISSN - 2193-3863
DOI - 10.35630/2199-885x/2022/12/2.6
Subject(s) - isotretinoin , acne , medicine , bioavailability , saliva , drug , dermatology , pharmacology
The aim of the work was to study the effect of isotretinoin preparations with different bioavailability (acnecutane and roaccutane) on blood and saliva crystallization in patients with severe forms of acne. The studies were conducted in two main groups: 25 patients used the drug Acnecutan in the treatment, 10 patients used the usual isotretinoin (Roaccutane). A study of the nature of own and initiated crystallization of blood serum and saliva was carried out by our techniques. The results of the study allow us to conclude that the tesicrystalloscopic "pattern" of the biological environment of patients with acne differs significantly from that characteristic of practically healthy people. Based on biocrystalloscopic testing, it was found that in the course of treatment with isotretinoin drugs, a partial normalization of indicators was observed, which occurs mainly when using Acnecutan.