Open AccessBIOCHEMICAL STUDY OF MENSTRUAL BLOOD AND A MATHEMATICAL MODEL FOR DIAGNOSIS OF UTERINE MYOMAS
Author(s) -
Yuliana Ukhanova,
A.R. Zoeva,
Olga Tishkova,
Svetlana Belyavskaya,
A. K. Ayupova,
Pavel Loginov
Publication year - 2021
Publication title -
archiv euromedica
Language(s) - English
Resource type - Journals
eISSN - 2199-885X
pISSN - 2193-3863
DOI - 10.35630/2199-885x/2021/11/2/g.1
Subject(s) - uterine fibroids , medicine , infertility , menstrual bleeding , outpatient clinic , menstrual cycle , uterus , gynecology , obstetrics , pregnancy , biology , hormone , genetics
Uterine myomas or fibroids (UF) are the most common tumors in women, which can cause serious complications, often require surgical interference and cause infertility. The authors proposed a comprehensive approach to solving this issue, which includes identifying the characteristic structures of the solid phase of menstrual discharge and the introduction of a mathematical model for predicting the growth rates of UF. Patients were divided into three groups of women of reproductive age. The control group included 41 relatively healthy patients. The second group consisted of 40 women with simple UF (group 1), and 30 women with proliferating UF were included in the third group (group 2). Development and implementation of a method for diagnosing UF, which includes the study of morphological structures of solid phase of menstrual blood and levels of ligands inducing apoptosis and proliferation, allows to find the most optimal solution for this clinical task. A mathematical model is proposed for predicting the growth rates of UF. The safety and atraumatic method of morphological analysis of menstrual fluids makes it possible to apply it effectively in the work of an outpatient clinic.