Open AccessTHE EFFECT OF ASSOCIATED CHRONIC OBSTRUCTIVE PULMONARY DISEASE ON THEINDICATORS OF PRECURSOR OFTYPE B NATURAURETIC PEPTIDE AND PROADRENOMEDULLIN AMONG PATIENTSWITH ISCHEMIC CA
Author(s) -
E. I. Myasoedova,
Л. П. Воронина,
Е. А. Попов,
И В Севостьянова,
G.N. Mukhambetova,
О. С. Полунина,
N.Y. Perova,
T. V. Prokofievа
Publication year - 2019
Publication title -
archiv euromedica
Language(s) - English
Resource type - Journals
eISSN - 2199-885X
pISSN - 2193-3863
DOI - 10.35630/2199-885x/2019/9/1/106
Subject(s) - medicine , pulmonary disease , concomitant , ischemic cardiomyopathy , cardiomyopathy , cardiology , disease , gastroenterology , heart failure , ejection fraction
The study showed that a statisticallysignificant increase of NT-proBNP levels (779,36 [473;2193] pg/ml) and MR-proADM (1,72 [1,56; 1,98] nmol/l)relative to the control values (69.90 [48.96; 91.00] pg / mland 0,49 [0,18; 0,58] nmol/l, respectively) is common forthe patients with ischemic cardiomyopathy. The presence ofconcomitant chronic obstructive pulmonary disease amongthe patients is associated with more pronounced increasein the level of NT-proBNP (872,37 [510; 2355] pg/ml) andMR-proADM (1,97 [1,75; 2,19] nmol/l) compared with agroup of patients with isolated ischemic cardiomyopathy.This can be considered as one of the compensation links forthis comorbid combination