Open AccessThe prevalence of different variants of Helicobacter pylori genotypes in families of patients with helicobacter-associated diseases
Author(s) -
K.M. Perfilova,
I.V. Shutova,
N.V. Neumoina,
M.V. Neumoina,
T.A. Troshina,
Т. Ю. Бутина,
И. В. Кузнецова
Publication year - 2019
Publication title -
zdorovʹe naseleniâ i sreda obitaniâ
Language(s) - English
Resource type - Journals
eISSN - 2619-0788
pISSN - 2219-5238
DOI - 10.35627/2219-5238/2019-321-12-66-70
Subject(s) - helicobacter pylori , gastritis , genotype , chronic gastritis , transmission (telecommunications) , pathogenicity island , pathogenicity , biology , immunology , medicine , gene , microbiology and biotechnology , genetics , genome , electrical engineering , engineering
The article presents the results of the examination of relatives of the patients with chronic H. pylori-associated gastritis. The genes of H. pylori pathogenicity were investigated by PCR to determine possible intrafamilial transmission of the infection. We established that in families of the patients with chronic gastritis, H. pylori was found in more than 60 % of relatives. The most similar spectrum of the genes of H. pylori pathogenicity was found in the samples of spouses, as well as in the mothers and the children. The study of H. pylori genovariant helps establish the mechanisms and ways of transmission of the infection, identify people infected with the microorganism with the most pronounced pathogenic potential and requiring therapy.