Open AccessEfecto del análogo de L-carnitina, la b-hidroxifosfocarnitina sobre el metabolismo de Nocardia brasiliensis
Author(s) -
Sandra Martínez-Robles,
Blanca Estela Jaramillo Loranca,
Erik González-Ballesteros,
Jorge ReyesEsparza,
Genaro Vargas-Hernández
Publication year - 2019
Publication title -
ecorfan ecuador journal
Language(s) - English
Resource type - Journals
ISSN - 1390-9959
DOI - 10.35429/eje.2019.11.6.15.20
Subject(s) - nocardia brasiliensis , microbiology and biotechnology , antimicrobial , biology , nocardia , chemistry , bacteria , nocardiosis , genetics
Objectives: To determine whether β-HFC, in addition to its immunomodulatory effect as a therapeutic alternative in the combat of the mycetoma has an effect on the biochemical activity of N. brasiliensis. Methodology: determination of bacterial growth using N. brasilensis in the presence of β-HFC and biochemical analysis of its metabolism. Contribution: The immunomodulatory function of β-HFC in the treatment of chronic infections has recently been studied but it is not known whether it also has any antimicrobial effect, so in this paper the direct effect of β-HFC in N. brasiliensis will be elucidated in part.