Open AccessSarcopenia and its Association with Geriatric Syndromes and Quality of Life in Older Indian Outpatients – A Cross-sectional Pilot Observational Study
Author(s) -
Sunny Singhal,
Gevesh Chand Dewangan,
Rishav Bansal,
Ashish Datt Upadhyay,
Sada Nand Dwivedi,
Chandan Jyoti Das,
Prasun Chatterjee,
Aparajit Ballav Dey,
Avinash Chakrawarty
Publication year - 2019
Publication title -
journal of the indian academy of geriatrics
Language(s) - English
Resource type - Journals
eISSN - 0974-3405
pISSN - 0974-2484
DOI - 10.35262/jiag.v15i2.66-74
Subject(s) - sarcopenia , medicine , osteoporosis , quality of life (healthcare) , geriatric depression scale , malnutrition , physical therapy , grip strength , dementia , gerontology , depression (economics) , cross sectional study , observational study , disease , cognition , psychiatry , pathology , depressive symptoms , nursing , economics , macroeconomics
Background: Despite the huge clinical impact of sarcopenia, there is very little to no data from Indian subcontinent regarding sarcopenia in older adults. We conducted this study to assess the frequency of sarcopenia in Indian older outpatients and its characteristics and associations with various geriatric syndromes and quality of life in Indian older adults. Methods: 100 participants above the age of 65 years were recruited from the outpatient department of Geriatric Medicine of a tertiary care hospital in India. Muscle mass, muscle strength and physical performance was measured by DXA scan (Dual Energy X-ray Absorptiometry), hand-held dynamometer and 4 m gait speed respectively. Sarcopenia was identified using an Asian working group for sarcopenia (AWGS) criteria. Many geriatric syndromes such as osteoporosis, dementia, depression and malnutrition were assessed using DXA scan (Dual Energy X-ray Absorptiometry), HMSE (Hindi Mental State Questionnaire), GDS-5 (Geriatric Depression scale – 5 item questionnaire) and MNA (Mini Nutritional Assessment) respectively. Quality of life was assessed using the OPQOL-brief questionnaire. Results: The preval nce of sarcopenia in our study population was 53% (49.3% in males, 61.3% in females). Hypothyroidism, neurological disease and osteoporosis were the only comorbidities found to be positively associated with sarcopenia. Among geriatric syndromes, nutrition and cognition were negatively associated with sarcopenia. Sarcopeniawas also negatively related to the quality of life. Multivariate stepwise logistic regression analysis showed that osteoporosis (OR: 5.43; 95% CI: 1.57-18.81; p-value: <0.01) was significantly associated with sarcopenia. Conclusion: Sarcopenia was common among Indian older outpatients with increased risk of geriatric syndromes and poor quality of life, therefore, a regular sarcopenia assessment may be considered in elderly patients.