Open AccessPolysaccharide Nanocapsules for Drug Delivery Applications, Current Status and Future Perspectives
Author(s) -
Marian Florea,
Rodica Mariana Ion
Publication year - 2021
Publication title -
the annals of "dunărea de jos" university of galaţi. fascicle ix, metallurgy and material science
Language(s) - English
Resource type - Journals
eISSN - 2668-4756
pISSN - 2668-4748
DOI - 10.35219/mms.2021.1.07
Subject(s) - nanocapsules , drug delivery , nanotechnology , drug , materials science , nanoparticle , chemistry , pharmacology , medicine
In recent years pharmaceutical formulations using polymeric nanocapsules have been widely studied for developing novel drug delivery strategies. Nanocapsules provide a unique core-shell nanostructure, consisting of a liquid/solid core surrounded by a polymeric shell. Natural or modified polysaccharides are prime candidates for use as building blocks of the nanocapsule shells, due to their demonstrated safety, versatility and low cost and to the fact that they are widely used as excipients in classical drug formulations. The aim of this paper is to present the recent advances in drug delivery strategies using polysaccharidic nanocapsules and to discuss future opportunities and challenges in developing modern pharmaceutical formulations using such systems.