Open AccessA five-year retrospective hospital-based study of endogenous endophthalmitis in south Malaysia
Author(s) -
Hayatulrizal Muhd,
Kiet Phang Ling,
Francesca Martina Vendargon
Publication year - 2020
Publication title -
malaysian journal of ophthalmology
Language(s) - English
Resource type - Journals
eISSN - 2665-9565
pISSN - 2665-9557
DOI - 10.35119/myjo.v2i1.99
Subject(s) - medicine , klebsiella pneumoniae , odds ratio , retrospective cohort study , endophthalmitis , confidence interval , visual acuity , medical record , diabetes mellitus , risk factor , surgery , biology , biochemistry , escherichia coli , gene , endocrinology
Purpose: To analyse the predisposing factors, microbial profiles, source of infection, and visual outcomes of endogenous endophthalmitis seen in Hospital Sultanah Aminah Johor Bahru (Johor, Malaysia).
Study design: Retrospective review.
Methods: The medical records of 15 patients, of which 19 eyes were diagnosed with endogenous endophthalmitis, admitted from January 2014 to December 2018 were retrospectively reviewed.
Results: The mean age was 55.9 ± 12.7 years (range: 31-78 years of age). There were four patients (26.7%) with bilateral involvement. Diabetes mellitus was the commonest risk factor in this study (odds ratio: 16; 95% confidence interval: 1.09-234.26). The most common source of infection was urosepsis (n = 3, 20%) followed by liver abscesses (n = 2, 13.3%), Klebsiella pneumoniae being the most common microorganism isolated (n = 4, 44.4%). Only 10.5% of eyes (n = 2) had a final Snellen visual acuity better than 6/60, while 47.4% of eyes (n = 9) had vision of no light perception.
Conclusion: In this study, Klebsiella pneumoniae was the most common organism. Overall, endogenous endophthalmitis is associated with poor visual outcomes.