Open AccessCases of cytomegalovirus retinitis in patients treated for cancer
Author(s) -
Marium Jamaluddin Ahmad,
Tengku Ain Kamalden,
Nurliza Khaliddin,
Tajunisah Iqbal
Publication year - 2020
Publication title -
malaysian journal of ophthalmology
Language(s) - English
Resource type - Journals
eISSN - 2665-9565
pISSN - 2665-9557
DOI - 10.35119/myjo.v2i1.96
Subject(s) - ganciclovir , immunosuppression , cytomegalovirus , retinitis , medicine , cytomegalovirus retinitis , blurred vision , cancer , surgery , human immunodeficiency virus (hiv) , ophthalmology , human cytomegalovirus , herpesviridae , virus , immunology , viral disease
Cytomegalovirus (CMV) retinitis is an opportunistic infection affecting immunocompromised patients. This case series describes 2 patients aged 19 and 10 years who were undergoing cancer treatment and were referred for complaints of worsening blurred vision. The retinal findings in the first patient showed multiple yellowishsubretinal areas with haemorrhages, while in the second patient there was presence of frosted branch angiitis. Confirmation of diagnosis was done using PCR of vitreous samples and blood CMV levels. Both tested negative for HIV. Both received intravitreal and systemic ganciclovir. It is important for ophthalmologists to consider CMVretinitis in all patients with any form of immunosuppression.