Open AccessEvaluation of anterior chamber volume using Pentacam and anterior segment optical coherence tomography among normal subjects
Author(s) -
Vijaya Anandan,
Rekha Srinivasan,
Rashima Asokan,
Ronnie George
Publication year - 2018
Publication title -
asian journal of ophthalmology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.111
H-Index - 5
eISSN - 2452-0691
pISSN - 1560-2133
DOI - 10.35119/asjoo.v16i2.367
Subject(s) - medicine , keratometer , ophthalmology , optical coherence tomography , gonioscopy , anterior chamber angle , nuclear medicine , limits of agreement , anterior eye segment , intraocular pressure , cornea
Aim: To compare the anterior chamber volume measurements obtained with Pentacam and derived from anterior segment optical coherence tomography.
Design: Cross-sectional study.
Methods: We included normal subjects who underwent a comprehensive eye examination including refraction, keratometry, Goldmann applanation tonometry, gonioscopy, anterior segment optical coherence tomography (AS-OCT) (Carl Zeiss Meditec Inc.; Dublin, CA, USA) and Pentacam (Oculus Inc.; Lynnwood, WA, USA). Fifty scans were selected for Pentacam and 12 images were selected for calculation of anterior chamber volume. Only the right eye was considered for analysis.
Results: One-hundred and nineteen eyes of 119 subjects were included for analysis. The mean age of the subjects was 42.58 ± 13.15 years, of which 74 were female and 45 were male. The mean anterior chamber volume measured using AS-OCT was 119.17 ± 26.56 mm3 and with Pentacam was 131.29 ± 34.26 mm3. The comparison of means between the two modalities was statistically significant (t = -8.857, Mean Difference (MD) = 12.11, 95% CI: (4.29, 19.95), p = 0.003). Bland-Altman plot showed poor agreement between the chamber volume measurements obtained by Pentacam and AS-OCT with MD of 12.1 mm3 (95 % CI: 41.4 to -17.1) and intra-class correlation between the two instruments was 0.94 (95% CI: 0.91, 0.96) (p < 0.0001).
Conclusion: The anterior chamber volume can be measured using Pentacam as well as AS-OCT since these measurements were reliable. However, these measurements were not interchangeable due to poor levels of agreement.