Open AccessMicroflora of upper parts of gastrointestinal tract during acute necrotizing pancreatitis
Author(s) -
Oleksandr Rotar,
Igor Khomiak,
Vasyl Rotаr,
Andrii Khomiak,
V. Shafraniuk,
O. Hrama
Publication year - 2019
Publication title -
sučasnì medičnì tehnologìï
Language(s) - English
Resource type - Journals
ISSN - 2072-9367
DOI - 10.34287/mmt.4(43).2019.11
Subject(s) - rifaximin , acute pancreatitis , gastroenterology , small intestine , medicine , ciprofloxacin , necrotizing pancreatitis , pathological , gastrointestinal tract , microbiology and biotechnology , biology , antibiotics
Analysis of results of treatment of 153 patients with acute necrotizing pancreatitis has been performed. Small intestinal content at admission, fluid and necrotic collections were gathered for microbiological investigation. At 57,4% of patients 8 strains of gramm negative microorgamisms were identified from small intestine before operation. Similar microflore were cultivated from pathological foci at 57,4% of patients after operation. Minimal inhibitory concentration of rifaximin from < 0,25 till 8 µg/ml and ciprofloxacin from 0,25 till 1 µg/ml suppressed growth of 100% of isolated microorganisms in vitro.