Active Fractions of Methanol Crude Obtained from Acacia Seyal Gum and their Antiproliferative Effects against Human Breast Cancer Cell Lines | Zendy

Ahmed Am Elnour | Zendy; Mohamed Elwathig Saeed Mirghani | Zendy; Nassereldeen Ahmed Kabbashi | Zendy; Djabir Daddiouaissa | Zendy; Khalid Hamid Musa | Zendy; Md. Zahangir Alam | Zendy; Abdurahman Hamid Nour | Zendy

Open Access

Active Fractions of Methanol Crude Obtained from Acacia Seyal Gum and their Antiproliferative Effects against Human Breast Cancer Cell Lines

Author(s) -

Ahmed Am Elnour,

Mohamed Elwathig Saeed Mirghani,

Nassereldeen Ahmed Kabbashi,

Djabir Daddiouaissa,

Khalid Hamid Musa,

Md. Zahangir Alam,

Abdurahman Hamid Nour

Publication year - 2020

Publication title -

global journal of human social science

Language(s) - English

Resource type - Journals

eISSN - 2249-4626

pISSN - 0975-5896

DOI - 10.34257/gjsfrcvol20is3pg51

Subject(s) - chemistry , acacia , human breast , methanol , chromatography , exudate , traditional medicine , cancer cell lines , acetone , botany , food science , cancer , biology , biochemistry , cancer cell , medicine , organic chemistry , genetics

Background: This study is on Acacia seyal gum, which is an exudate from Talha (Acacia seyal) tree. It provides a rich source of prebiotic that is used traditionally in folk medicine. Aims: The anti-proliferative effect (APE) of Acacia seyal gum (ASG) and Prebio-T-commercial (PTC) samples on human breast cancer (MCF-7) cell lines, and their antioxidant activities (AA) were investigated. Methods: The methanol crude extracts of both Acacia seyal gum and Prebio-T- commercial were fractioned into acetone and methanol, respectively. The anti-proliferative effect on human breast cancer cell lines for each fraction was examined using sulphorhodamine assay (SRB assay). Methanol crude extracts and their active compositions were analysed carefully using Gas chromatography-mass spectrometry technique.

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