Open AccessNonspecific skin lesions in malignant lymphomas
Author(s) -
A. O. Rukavitsyn,
I. Lamotkin,
О.А. Рукавицын,
Andrey Lamotkin
Publication year - 2020
Publication title -
tihookeanskij medicinskij žurnal
Language(s) - English
Resource type - Journals
ISSN - 1609-1175
DOI - 10.34215/1609-1175-2020-4-76-80
Subject(s) - mycosis fungoides , medicine , pathology , pathognomonic , lymphoma , skin lesion , chronic lymphocytic leukemia , dermatology , leukemia , disease , immunology
Objective: Clinical characteristics of the peculiarities of non-specific skin lesions with patients having malignant lymphomas (ML). Methods : 130 patients having malignant lymphomas were observed, 50 patients – having Hodgkin’s lymphomas, 38 patients - B-cell lymphomas and 42 patients – T-cell lymphomas. Results : Six main types of nonspecific lesions are defined among patients having malignant lymphomas: 1) skin lesions of auto toxic genesis, 2) skin lesions determined with vascular pathology, 3) skin lesions due to hemolysis and hemostatic disorders, 4) skin lesions of those having cryoglobulinemia/cryofibrinogenemia, 5) skin lesions due to metabolic disorder, 6) infectious diseases. Conclusions : Lesions of auto toxic genesis and infectious diseases prevail among nonspecific skin changes when having malignant lymphomas. Patients having Hodgkin’s lymphomas experience dermal itching more often. Among B-cell lymphomas skin lesions are more pathognomonic for chronic lymphocytic leukemia, among T-cell lymphomas – for fungal mycosis. Nonspecific skin lesions, having arisen before typical clinical picture of malignant lymphomas allow to suspect and diagnose the main illness on time. Disappearance of skin lesions against the background of specific therapy can bear evidence to the efficiency of the malignant lymphomas’ treatment.